Key result
Mean platelet volume was significantly higher in patients with type 2 diabetes compared to non-diabetic controls (10.07 vs 7.47 fl, p<0.001) and in diabetics with vascular complications.
Why the study?
Is mean platelet volume associated with type 2 diabetes mellitus and its vascular complications?
Population
266 subjects at B.P Koirala Institute of Health Sciences
Design
Cross-sectional
Authors
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Elevated MPV may support risk stratification in T2DM; leaves open prospective validation before clinical adoption.
Cross-Sectional (n=266)
No
Is mean platelet volume associated with type 2 diabetes mellitus and its vascular complications?
Absolute Event Rate: 10.07% vs 7.47%
p-value: p=<0.001
Mean platelet volume is significantly elevated in patients with type 2 diabetes, particularly those with vascular complications, suggesting its potential as a cost-effective biomarker for early detection.
Thakur et al. (2023) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=266). Type 2 Diabetes Mellitus vs. Non-diabetic controls was evaluated on Mean platelet volume (MPV) (p=<0.001). Mean platelet volume was significantly higher in patients with type 2 diabetes compared to non-diabetic controls (10.07 vs 7.47 fl, p<0.001) and in diabetics with vascular complications.
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