Key result
Poor glycemic control in diabetes is linked to ~7% higher mean platelet volume.
Why the study?
Mean platelet volume is considered to impact the development of microvascular complications in diabetes mellitus, prompting investigation into its association with nephropathy, retinopathy, and glycemic parameters.
Is mean platelet volume associated with glycemic control and microvascular complications in patients with diabetes mellitus?
Population
200 patients seeking medical attention for newly or previously diagnosed DM
Design
Observational study
Authors
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Does not support MPV-guided diabetes care; leaves open its role in microvascular risk prediction.
Observational (n=200)
No
Is mean platelet volume associated with glycemic control and microvascular complications in patients with diabetes mellitus?
Absolute Event Rate: 9.21% vs 8.58%
p-value: p=0.002
Higher mean platelet volume is associated with poor glycemic control and microalbuminuria in patients with diabetes mellitus.
Manvar et al. (2022) conducted an observational in Diabetes mellitus (n=200). Poor glycemic control (HbA1c >8%) vs. Good to moderate glycemic control (HbA1c <8%) was evaluated on Mean platelet volume (MPV) (p=0.002). Poor glycemic control in diabetic patients was associated with a significantly higher mean platelet volume (9.21 fL) compared to good glycemic control (8.58 fL, p=0.002).
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