Key result
Type 2 diabetes mellitus was associated with a significantly higher mean platelet volume compared to nondiabetic subjects (8.29 vs 7.47 fl; P=0.001).
Why the study?
Is mean platelet volume higher in patients with Type 2 diabetes mellitus compared to nondiabetic subjects?
Population
300 Type 2 diabetic patients and 300 nondiabetic subjects
Comparison
Type 2 Diabetes Mellitus vs Nondiabetic subjects
Design
Case-control
Authors
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MPV elevation may mark vascular risk in T2DM; hypothesis-generating and should not change practice without prospective data.
Case-Control (n=600)
Is mean platelet volume higher in patients with Type 2 diabetes mellitus compared to nondiabetic subjects?
Absolute Event Rate: 8.29% vs 7.47%
p-value: p=0.001
Mean platelet volume is significantly elevated in Type 2 diabetes and correlates with glycemic control, suggesting its potential utility as a simple marker for vascular risk.
Kodiatte et al. (2012) conducted a case-control in Type 2 Diabetes Mellitus (n=600). Type 2 Diabetes Mellitus vs. Nondiabetic subjects was evaluated on Mean platelet volume (MPV) (p=0.001). Type 2 diabetes mellitus was associated with a significantly higher mean platelet volume compared to nondiabetic subjects (8.29 vs 7.47 fl; P=0.001).
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