Key result
Mean platelet volume was significantly higher in patients with type II diabetes mellitus (8.83 fl) compared to non-diabetic controls (7.62 fl) and positively correlated with HbA1c and fasting blood sugar.
Why the study?
Is mean platelet volume elevated in type II diabetes mellitus and does it correlate with glycemic control and diabetic complications?
Population
400 participants, comprising 200 patients with type II diabetes mellitus and 200 non-diabetic control…
Comparison
Measurement of Mean Platelet Volume and other… vs Non-diabetic control subjects.
Design
Cohort
Authors
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Should not yet change T2DM monitoring; leaves open MPV as a glycemic biomarker pending prospective validation.
Case-Control (n=400)
No
Is mean platelet volume elevated in type II diabetes mellitus and does it correlate with glycemic control and diabetic complications?
Absolute Event Rate: 8.83% vs 7.62%
p-value: p=<0.001
Navya et al. (2015) conducted a case-control in Type II Diabetes Mellitus (n=400). Type II Diabetes Mellitus vs. Non-diabetic controls was evaluated on Mean Platelet Volume (fl) (p=<0.001). Mean platelet volume was significantly higher in patients with type II diabetes mellitus (8.83 fl) compared to non-diabetic controls (7.62 fl) and positively correlated with HbA1c and fasting blood sugar.
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