Answers are grounded in this paper and cite their sources.
A new, simple and repeatable liquid chromatography method with charged aerosol detection (LC-CAD) for the determination of gentamicin sulphate composition and related substances has been developed. Gentamicin lacks of chromophores, therefore its determination is quite problematic. Using a universal CAD enables to achieve good separation without sample derivatization. Mass spectrometry was employed to confirm the LC-CAD peak profile. The proposed method was validated and applied for the determination of gentamicin sulphate composition and related substances in pharmaceutical preparations.
No takes yet. Share an insight, caveat, or question.
Stypułkowska et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: