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Arterial infarct implantation to tumors is suggested as a logical extension of selective arterial perfusion of tumors with chemotherapeutic agents. The arterial bed of a tumor provides an arborized system which allows the distribution of infarct particles to various areas of the tumor, while the propensity of arteries to respond to infarction by means of spasm, as well as the resulting preferential flow to other areas, facilitates a geometric distribution of infarct sources. The author's experience in the treatment of 20 patients with hypernephroma and 12 patients with advanced pelvic neoplasms is described.
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Erich K. Lang (1971) studied this question.
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