Multifunctional metal complexes with mixed ligands: Synthesis, computational insights, and antimicrobial potential

In order to create novel mixed ligand transition metal-based coordination compounds, several 2-hydroxy-benzaldehyde derivatives interacted with Schiff bases based on the sulfa drug. The spectroscopic properties and antibacterial properties of the generated compounds and their coordination compounds were studied in detail. The ligands were structurally characterized using 1H-NMR, IR, mass spectrometry, UV-Vis spectroscopy, and elemental analysis, while the coordination compound’s structure was verified by IR, UV-Visible, and FAB mass spectroscopy. In vitro studies were conducted to assess the effectiveness of the ligands and coordination compounds against Gramme + ve bacteria (B. subtilis, S. epidermidis), Gramme -ve bacteria (E. coli, P. aeruginosa), and fungus (A. niger). The findings highlight the potential of coordination compounds based on transition metals and the necessity for more study in this field.