Key result
CO2 laser excision of a malignant fibrous histiocytoma of the vocal fold resulted in the patient remaining recurrence-free at 3 years of follow-up.
Case Report (n=1)
CO2 laser excision with vocal fold preservation was successful in treating a rare case of malignant fibrous histiocytoma of the vocal fold, with no recurrence at 3 years.
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May support CO2 laser excision for rare vocal fold MFH; hypothesis-generating and requires prospective validation.
Malignant fibrous histiocytoma, also known as pleomorphic undifferentiated sarcoma not otherwise specified, arises in numerous organs. The first-line treatment is complete excision of the mass, but in some cases postoperative chemo- and/or radiotherapy is recommended. Only a few cases of malignant fibrous histiocytoma of the vocal fold have been previously reported in the literature. We report a new case, which originated in the true vocal fold of a 65-year-old man. The mass was removed via CO2 laser excision with preservation of the vocal fold and without the need for further treatment. At 3 years of follow-up, the patient remained recurrence-free.
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Kim et al. (2015) conducted a case report in Malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma NOS) of the vocal fold (n=1). CO2 laser excision was evaluated on Recurrence. CO2 laser excision of a malignant fibrous histiocytoma of the vocal fold resulted in the patient remaining recurrence-free at 3 years of follow-up.
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