Answers are grounded in this paper and cite their sources.
The "ligandless" palladium acetate-catalyzed Suzuki cross-coupling reaction of ArX with aryl- and vinylboronic acids in water without organic cosolvent in the presence of tetrabutylammonium bromide is reported. Aryl bromides give high yields and considerably accelerate the coupling. A wide variety of functional groups can be tolerated. Aryl iodides, however, give incomplete conversion and aryl triflate coupling shows no improvement over reported conditions.
No takes yet. Share an insight, caveat, or question.
Badone et al. (1997) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: