Key result
High preoperative risk in patients undergoing endovascular repair of AAAs was associated with higher 30-day perioperative mortality compared to acceptable risk (15.7% vs 3.7%, p=0.02).
Why the study?
What are the perioperative and late mortality rates following endovascular repair of abdominal aortic aneurysms in high-risk versus acceptable-risk patients?
Cohort (n=221)
What are the perioperative and late mortality rates following endovascular repair of abdominal aortic aneurysms in high-risk versus acceptable-risk patients?
Answers are grounded in this paper and cite their sources.
Perioperative mortality following endovascular repair of abdominal aortic aneurysms is substantially higher in high-risk patients compared to those at acceptable risk.
PURPOSE: To present the perioperative and late mortality following endovascular repair (EVR) of abdominal aortic aneurysms (AAAs). METHODS: Data were collected prospectively on 221 patients undergoing AAA EVR over a 4-year period (median 5-month follow-up). Patients were classified preoperatively as high risk with at least 1 of these features: serum creatinine > 150 micromol/L, ischemic heart disease or poor left ventricular function, respiratory function < 50% of predicted normal, ruptured or symptomatic AAA, contraindication to or failed open repair, and age > 80 years. RESULTS: One hundred forty (63.3%) patients were classified as high risk, the most common criterion being cardiac disease (n = 96, 68.6%). There were 25 (11.3%) deaths in the 30-day perioperative period, 22 (15.7%) in the high-risk group compared to 3 (3.7%) in the acceptable-risk group (p = 0.02). The most common causes of perioperative death were multisystem organ failure and myocardial infarction. A further 21 (9.5%) late deaths occurred, 16 (11.4%) in the high-risk group and 5 (6.2%) in the acceptable-risk group (p > 0.1). CONCLUSIONS: The mortality of patients at acceptable risk undergoing EVR compares with the best published series for conventional open AAA repair. The perioperative and late mortality in the high-risk patients are substantially higher.
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Walker et al. (1999) conducted a cohort in Abdominal aortic aneurysms (n=221). High preoperative risk vs. Acceptable preoperative risk was evaluated on 30-day perioperative mortality (p=0.02). High preoperative risk in patients undergoing endovascular repair of AAAs was associated with higher 30-day perioperative mortality compared to acceptable risk (15.7% vs 3.7%, p=0.02).
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