Key result
Stent barbs and hooks increased the fixation of stent-grafts tenfold compared to stents without hooks and barbs (median displacement force 22.5 N vs 2.5 N, p<0.001).
Why the study?
Do stents with hooks and barbs improve stent-graft fixation in the abdominal aorta compared to stents without hooks and barbs?
Do stents with hooks and barbs improve stent-graft fixation in the abdominal aorta compared to stents without hooks and barbs?
Absolute Event Rate: 22.5% vs 2.5%
p-value: p=<0.001
Stent barbs and hooks significantly increase the fixation strength of stent-grafts in cadaveric aortas, which may help prevent migration after endovascular aneurysm repair.
Supports barbed stent-grafts for EVAR fixation; leaves open clinical impact on migration.
Purpose: To investigate if stents with hooks and barbs will improve stent-graft fixation in the abdominal aorta. Methods: Sixteen- to 24-mm-diameter Dacron grafts were deployed inside cadaveric aortas. The grafts were anchored by stents as in endovascular abdominal aortic aneurysm repair. One hundred thirty-seven stent-graft deployments were carried out with modified self-expanding Z-stents with (A) no hooks and barbs (n = 75), (B) 4 5-mm-long hooks and barbs (n = 39), (C) 8 10-mm-long, strengthened hooks and barbs (n = 19), or (D) hooks only (n = 4). Increasing longitudinal traction was applied to determine the displacement force needed to extract the stent-grafts. The radial force of the stents was measured and correlated to the displacement force. Results: The median (interquartile range) displacement force needed to extract grafts anchored by stent A was 2.5 N (2.0 to 3.4), stent B 7.8 N (7.4 to 10.8), and stent C 22.5 N (17.1 to 27.9), p < 0.001. Both hooks and barbs added anchoring strength. During traction, the weaker barbs were distorted or caused intimal tears. The stronger barbs engaged the entire aortic wall. The radial force of the stents had no impact on fixation, while aortic calcification and graft oversizing had marginal effects. Conclusions: Stent barbs and hooks increased the fixation of stent-grafts tenfold, while the radial force of stents had no impact. These data may prove important in future endograft development to prevent stent-graft migration after aneurysm exclusion.
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Malina et al. (1998) studied Abdominal aortic aneurysm (n=137). Stents with hooks and barbs vs. Stents with no hooks and barbs was evaluated on Displacement force needed to extract the stent-grafts (p=<0.001). Stent barbs and hooks increased the fixation of stent-grafts tenfold compared to stents without hooks and barbs (median displacement force 22.5 N vs 2.5 N, p<0.001).
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