Key result
Intramuscular administration of midazolam was associated with a reported case of cardiorespiratory arrest and death.
Case Report (n=1)
This case report highlights a rare but fatal safety signal of cardiorespiratory arrest and death associated with intramuscular midazolam administration.
Raises caution for IM midazolam; case report leaves causal association open for confirmation.
Midazolam hydrochloride is commonly used for dental or endoscopic procedures. Although generally consisted safe when given intramuscularly, intravenous administration is known to cause respiratory and cardiovascular depression. This report describes the first published case of cardiorespiratory arrest and death associated with intramuscular administration of midazolam. Information regarding midazolam use is reviewed to provide recommendation for safe administration.
No takes yet. Share an insight, caveat, or question.
Taylor et al. (1990) conducted a case report in Cardiorespiratory arrest (n=1). Intramuscular midazolam was evaluated on Cardiorespiratory arrest and death. Intramuscular administration of midazolam was associated with a reported case of cardiorespiratory arrest and death.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: