Key result
Coronary blood redox potential changes reflect cellular alterations within the heart muscle.
Why the study?
Alterations in cardiac metabolism in man or intact animals are difficult to assess due to limitations of arteriovenous balance studies and the need for steady state conditions.
Design
Review of metabolic and redox potential changes in heart muscle
Authors
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May support blood-based myocardial metabolic assessment; leaves open prospective validation before clinical use.
Changes in the redox potential of blood perfusing the heart muscle can be utilized to investigate intermediary metabolism and alterations accompanying myocardial disease.
Gudbjarnason et al. (1962) conducted a review in Myocardial disease. Redox potential measurement was evaluated. Changes in the redox potential of a certain redox system in the blood perfusing the heart muscle reflect alterations within the heart muscle cell.
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