Key result
Hippocampal and cingulate lesions in rats impaired passive avoidance, while hippocampal lesions also reduced crouching responses, suggesting crouching disruptions may influence passive avoidance.
Rodent lesion effects highlight behavioral confounds in avoidance tasks; leaves open translation to human anxiety models.
The proportions of crouching responses after shock and the number of passive avoidance errors were compared for rats with lesions in the hippocampus, septum, or cingulum and their controls. Hippocampal lesioned Ss made fewer crouching responses and were poorer in passive avoidance. Septal lesions disrupted both crouching and locomotion but did not alter passive avoidance. The cingulate lesioned Ss were poorer on passive avoidance but their crouching decrease was not statistically significant. The results were interpreted as indicating that lesion-produced disruptions of crouching may influence passive avoidance performance.
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Blanchard et al. (1968) studied this question. Lesions in the hippocampus, septum, or cingulum vs. Controls was evaluated on Proportions of crouching responses after shock and the number of passive avoidance errors. Hippocampal and cingulate lesions in rats impaired passive avoidance, while hippocampal lesions also reduced crouching responses, suggesting crouching disruptions may influence passive avoidance.
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