Key result
Osteogenesis imperfecta patients undergoing non-cardiac surgery experienced mild intraoperative hyperpyrexia that did not differ significantly from matched controls (P=0.589).
Why the study?
Do patients with osteogenesis imperfecta have a higher risk of perioperative complications and intraoperative hyperthermia compared to controls?
Population
49 patients with osteogenesis imperfecta undergoing 180 anaesthetics, including a subset of 31 non-cardiac…
Comparison
Anaesthesia during surgery vs Patients without osteogenesis imperfecta
Design
Cohort
Follow-up
perioperative/intraoperative
Authors
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No excess hyperthermia risk apparent in osteogenesis imperfecta; leaves open confirmation in larger prospective cohorts.
Observational (n=49)
Do patients with osteogenesis imperfecta have a higher risk of perioperative complications and intraoperative hyperthermia compared to controls?
p-value: p=0.589
Patients with osteogenesis imperfecta undergoing non-cardiac surgery do not appear to have an increased risk of intraoperative hyperthermia or anaesthesia-related complications compared to patients without the condition.
Bojanić et al. (2011) conducted an observational in Osteogenesis imperfecta (n=49). Osteogenesis imperfecta vs. Controls without osteogenesis imperfecta was evaluated on Intraoperative temperature (p=0.589). Osteogenesis imperfecta patients undergoing non-cardiac surgery experienced mild intraoperative hyperpyrexia that did not differ significantly from matched controls (P=0.589).
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