Key result
A 22-year-old woman developed onychomadesis and a Staphylococcus aureus nail infection two months after contracting hand-foot-mouth disease, which was successfully treated with antibiotic therapy.
Case Report (n=1)
Highlights a rare case of onychomadesis and secondary bacterial infection following hand-foot-mouth disease in an adult.
Hand-foot-mouth disease is a viral disease that occurs mostly in children, but sometimes affects adults as well. It is most often caused by Coxsackie virus A16 or Enterovirus 71. Other strains of these viruses can also be an etiological factor for the development of the disease. It usually starts with an increase in body temperature and fatigue. Subsequently, papulo-vesicular rashes appear on the oral mucosa, palms and soles. Over time, some of them form small erosions or ulcers. Although rare, few weeks after an infection has passed, nail changes can be seen. Some are associated with falling off the nail plate, others with onychomаdеsis or the development of a bacterial and/or fungal infection. In this report, we present a clinical case of a 22-year-old woman who in the month of September 2022 had hand-foot-mouth disease and two months later developed nail changes associated with a change in the integrity and color of the nail plate.
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Zh et al. (2023) conducted a case report in Hand-foot-mouth disease with subsequent onychomadesis and Staphylococcus aureus nail infection (n=1). Amoxicillin/clavulanic acid and topical fusidic acid was evaluated on Clinical improvement of nail changes. A 22-year-old woman developed onychomadesis and a Staphylococcus aureus nail infection two months after contracting hand-foot-mouth disease, which was successfully treated with antibiotic therapy.
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