Key result
Stent-supported angioplasty resulted in a significantly larger minimal luminal diameter compared to balloon angioplasty alone (3.4 vs 2.4 mm, p<0.01) in patients with acute myocardial infarction.
Why the study?
Does stent-supported angioplasty improve angiographic outcomes in patients with acute myocardial infarction and suboptimal balloon angioplasty results?
Cohort (n=32)
No
Does stent-supported angioplasty improve angiographic outcomes in patients with acute myocardial infarction and suboptimal balloon angioplasty results?
Mean Difference: 1
Absolute Event Rate: 3.4% vs 2.4%
p-value: p=<0.01
Stent-supported angioplasty is a safe and feasible supportive therapeutic strategy that yields excellent angiographic results for acute myocardial infarction patients with suboptimal outcomes after initial balloon angioplasty.
May support stenting after suboptimal balloon angioplasty in AMI; leaves open randomized confirmation of clinical outcomes.
Background:Although the superior reperfusion and improved clinical outcome following angioplasty for acute myocardial infarction (AMI) have been well known, 10 to 15% of reinfarction and recurrent ischemia in hospital are main limitation of primary percutaneous transluminal coronary angioplasty (PTCA).This study was undertaken to examine the safety and feasibility of stent-supported primary angioplasty in acute myocardial infarction.Methods:Between July 1995 and Jun.1997, 32 patients underwent direct or rescue PTCA, including patients with cardiogenicc shock.After PTCA, stentingwas attempted in patient with dissection or having more than 30% of residual stenosis.Result:In patient with direct PTCA, angiographic success rate was obtained in 91%(30/32).Stenting was attempted in 15 of 30 patients.These patients had suboptimal results (8 patients), nonocclusive dissection (3 patients) and acute occlusion (2 patient).Thrombolysis in myocardial infarction (TIMI) grade 3 flow was restored in 28 patients (93%).In one patient no-reflow phenomena was observed following stent insertion.Despite intra-aortic balloon pumping, there was one death during the hopitalization due to cardiogenic shock following PTCA.Subacute stent thrombosis developed in two patients.27 patients (90%) were event-free and clinically improved through out the follow up period (11.5±5.2 month).Quantitative angiography showed excellent angiographic result after stenting compared with balloon PTCA (2.4±0.6 mm vs. 3.4±0.3mm p<0.01).Conclusion:After failure of initial angioplasty, coronary stenting can be a supportive therapeutic strategy.Coronary stenting results in a high degree of angiographic success, a low incidence of subacute thrombosis.( ( ( (Korean Circulation J 1998 ; 28( ( ( (7) ) ) ) : 1185-1191) ) ) ) KEY WORDS:Acute myocardial infarction•Stent-supported angioplasty. 서 론급성
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Choi et al. (1998) conducted a cohort in Acute Myocardial Infarction (n=32). Stent-supported angioplasty vs. Balloon angioplasty alone was evaluated on Minimal luminal diameter (MLD) (p=<0.01). Stent-supported angioplasty resulted in a significantly larger minimal luminal diameter compared to balloon angioplasty alone (3.4 vs 2.4 mm, p<0.01) in patients with acute myocardial infarction.
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