Helical chirality can be imprinted onto a 2,2′-dihydroxybenzophenone derivative (see picture) in a highly stereospecific manner. A single amino acid combines with the receptor to form an imine with two internal hydrogen bonds. The azo group allows sensing of amino acid enantiopurity by circular dichroism spectroscopy.
No takes yet. Share an insight, caveat, or question.
Kim et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: