Key result
A fixed triple combination of perindopril, indapamide, and amlodipine expands therapeutic options and improves adherence for the treatment of arterial hypertension.
A fixed triple combination of perindopril, indapamide, and amlodipine expands therapeutic options and may increase patient adherence in the treatment of arterial hypertension.
May support fixed combinations for better BP control; leaves open need for randomized confirmation.
The management of patients with arterial hypertension is a difficult problem even if use the modern antihypertensive drugs. The reasons of the inadequate control to arterial pressure level during the treatment are different. The application fixed combinations of antihypertensive drugs improves the results of therapy, weigh with separate pathogenetic mechanisms of blood pressure increasing and the counterregulatory effects of the treatment each components of the combination. The use of fixed combinations significantly increases patient adherence to treatment. A new fixed triple combination of perindopril, indapamide, amlodipine expands therapeutic options for the treatment arterial hypertension. The effectiveness of the use of each of the components and their combination is proved in large international studies.
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Е. А. Темникова (2017) conducted a review in arterial hypertension. Fixed triple combination of perindopril, indapamide, and amlodipine was evaluated. A fixed triple combination of perindopril, indapamide, and amlodipine expands therapeutic options and improves adherence for the treatment of arterial hypertension.
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