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March 23, 2017International Journal of Blood Transfusion and ImmunohematologyOpen Access

The prevalence of transfusion transmitted infections: A focus on hepatitis B virus among blood donors at Hawassa blood bank center, Southern Ethiopia

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Authors

FBFisseha BonjaHawassa UniversityMHMintewab HusseinAddis Ababa UniversityJAJemal AlemuArmauer Hansen Research Institute

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Implication

Cross-sectional study reveals a 7.29% rate of transfusion-transmitted infections in blood donors, highlighting hepatitis B virus as the primary driver of blood unit discards.

Key Points

  • To evaluate the prevalence and risk factors of transfusion-transmitted infections among blood donors, with a specific focus on hepatitis B virus.
  • Conducted a cross-sectional study of N=384 voluntary and replacement blood donors from April to May 2015 at the Hawassa blood bank center in Southern Ethiopia.
  • Tested donor sera for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis, and analyzed Giemsa-stained thick blood smears for malaria.
  • Overall transfusion-transmitted infection prevalence was 7.29% (28/384), led by HBV at 4.2% (16/384), HIV at 1.6% (6/384), syphilis at 0.8% (3/384), HCV at 0.5% (2/384), and malaria at 0.3% (1/384).
  • Co-infections were detected in 0.5% (2/384) of donors, leading to a 7.14% discard rate of collected blood units, with HBV accounting for 57.1% of all discarded units.
  • Infection prevalence was significantly elevated among replacement and family donors at 16.1% compared to other donor categories (p = 0.039).

Cite This Study

Bonja et al. (2017) studied this question.

synapsesocial.com/papers/6a939f5904d7c7946bb851c1https://doi.org/10.5348/ijbti-2017-29-oa-2
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