What question did this study set out to answer?

To examine the structural causes behind the lack of innovation success in total hip replacements compared to the classic cemented Charnley design and propose a scientific framework for future development.

January 1, 1993Acta Orthopaedica ScandinavicaOpen Access

Failed innovation in total hip replacement: Diagnosis and proposals for a cure

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To examine the structural causes behind the lack of innovation success in total hip replacements compared to the classic cemented Charnley design and propose a scientific framework for future development.
Conducted a narrative review analyzing the predominant failure mechanisms of total hip replacement prostheses and fixation techniques.
Evaluated the orthopedic innovation cycle, assessing component design trade-offs, clinical trial practices, and marketing authorization standards.
No contemporary hip prosthesis design or fixation method achieved superior long-term clinical endurance over the traditional cemented Charnley concept.
Identified three major causes for innovation failure: conflicting design requirements among failure prevention scenarios, an unscientific surgical culture relying on trial-and-error, and ineffective implant market regulations.
Proposed a generic failure scenario framework combining systematic design evaluation, pre-clinical testing, and structured clinical trials to enable community-wide self-regulation.

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Implication

Review article identifies systemic causes of device failure in total hip replacement, highlighting the need for standardized pre-clinical testing and regulatory reform.

Cite This Study

R. Huiskes (1993) studied this question.

synapsesocial.com/papers/6a93a28f2cf12ee0be6973d8 https://doi.org/10.3109/17453679308994602

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Implication

Review article identifies systemic causes of device failure in total hip replacement, highlighting the need for standardized pre-clinical testing and regulatory reform.

Failed innovation in total hip replacement: Diagnosis and proposals for a cure

Key Points

Discussion

Implication

Cite This Study

Failed innovation in total hip replacement: Diagnosis and proposals for a cure

Key Points

Discussion

Implication

Cite This Study

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