Key result
Survival free from cardiac death over a median of 6 years was lower for acute myocardial infarction (84%) compared to unstable angina (92%) and new exertional angina (94%).
Cohort (n=537)
No
Survival free from cardiac death is similar between unstable angina and new exertional angina, but lower for acute myocardial infarction, highlighting the need for prompt management of new exertional angina.
Comparable cardiac survival in new exertional angina and unstable angina supports equivalent urgency; leaves open optimal intervention thresholds in observational cohorts.
BACKGROUND: Data on the contemporary mortality of coronary heart disease (CHD) are surprisingly sparse. AIM: To describe the contemporary mortality of all manifestations of CHD. DESIGN: Prospective follow-up of patients with a first presentation of CHD in a defined population. METHODS: We studied 537 patients with a first presentation of acute myocardial infarction, unstable angina or new exertional angina in Bromley Health Authority, London (population 295,000). Patients were prospectively monitored for cardiac and non-cardiac mortality for a median of 6 years. RESULTS: During a median 6 years follow-up, there were 88 (16%) deaths. Survival free from cardiac death was not significantly different between unstable angina (92%) and new exertional angina (94%), but was lower for acute myocardial infarction (84%). DISCUSSION: Mortality from CHD appears to be falling. However, efforts to prevent myocardial infarction should continue to be a priority, because on-going early mortality remains high. New exertional angina should be diagnosed and managed promptly, as its mortality is similar to that of unstable angina.
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Kevin Fox (2006) conducted a cohort in Coronary heart disease (n=537). Acute myocardial infarction vs. Unstable angina or new exertional angina was evaluated on Survival free from cardiac death. Survival free from cardiac death over a median of 6 years was lower for acute myocardial infarction (84%) compared to unstable angina (92%) and new exertional angina (94%).
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