Key result
Over a 20-year period, the rate of major coronary events in British men declined by an age-adjusted annual relative change of -3.6% (95% CI -4.8% to -2.4%; P<0.001).
Population
7,735 British men, aged 40-59 at entry, randomly selected from one general practice in each of 24 British…
Design
Cohort
Follow-up
20 years
Authors
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Suggests progress in preventing major events among British men; leaves open whether overall first coronary heart disease incidence has declined.
Cohort (n=7,735)
Yes
Effect estimate: Annual relative change -3.6% (95% CI -4.8% to -2.4%)
p-value: p=< 0.001
Over a 20-year period, a substantial decline in major coronary events among British middle-aged men was largely offset by an increase in diagnosed angina, resulting in little change in the overall incidence of first diagnosed coronary heart disease.
Lampe et al. (2005) conducted a cohort in Coronary heart disease (n=7,735). Time period (1978 to 2000) was evaluated on Trends in the rates of major coronary events (Annual relative change -3.6%, 95% CI -4.8% to -2.4%, p=< 0.001). Over a 20-year period, the rate of major coronary events in British men declined by an age-adjusted annual relative change of -3.6% (95% CI -4.8% to -2.4%; P<0.001).
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