Key result
Over a 12-month follow-up, common carotid artery median IMT in HIV-1-infected patients significantly increased by 0.020 mm (95% CI 0.012-0.029; P<10^-4).
Cohort (n=346)
Yes
Mean Difference: 0.02 (95% CI 0.012–0.029)
Absolute Event Rate: 0.56% vs 0.54%
p-value: p=<10(-4)
Carotid IMT increases slightly over 1 year in HIV-1-infected patients, driven primarily by conventional cardiovascular risk factors and baseline CD4 cell count.
No takes yet. Share an insight, caveat, or question.
Modest IMT progression was associated with conventional risks and CD4 count in HIV; hypothesis-generating for targeted strategies, should not yet change practice.
Mercié et al. (2005) conducted a cohort in HIV-1 infection (n=346). Time (1-year follow-up) vs. Baseline was evaluated on common carotid artery (CCA) median IMT (MD 0.020 mm, 95% CI 0.012-0.029, p=<10(-4)). Over a 12-month follow-up, common carotid artery median IMT in HIV-1-infected patients significantly increased by 0.020 mm (95% CI 0.012-0.029; P<10^-4).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: