Key result
The head-up tilt test, utilizing baseline tilt followed by isoprenaline provocation, successfully yielded a positive diagnosis of vasovagal syncope in 62.5% of patients with unexplained syncope.
Why the study?
Does the head-up tilt test with isoprenaline effectively and safely diagnose the cause of syncope in patients with unexplained syncope or presyncope?
Cross-Sectional (n=72)
No
Does the head-up tilt test with isoprenaline effectively and safely diagnose the cause of syncope in patients with unexplained syncope or presyncope?
The head-up tilt test with isoprenaline is a safe and effective non-invasive diagnostic tool, yielding a positive diagnosis in 62.5% of patients with unexplained syncope.
HUTT may aid diagnosis in undiagnosed syncope; leaves open need for randomized trials on yield and safety.
Background: Recurrent syncope is a distressing symptom in which the cause may remain undetermined. A definitive diagnosis may help the patients to lead a normal life and avoid the unnecessary risk to their lives. Objective: To evaluate the effectiveness and safety of Head up Tilt Test (HUTT) in patients with undiagnosed syncope and to detect and follow up any complications arising out of the procedure. Material and methods: The head up tilt table test was performed in department of cardiology. 72 patients with a history of syncope or presyncope underwent upright tilt table testing to exclude vasovagal syncope, with baseline tilt and if negative followed by progressively increasing doses of isoprenaline infusion. 70 tilt was used and continuous heart rate and non-invasive BP recordings were made every 2 minutes or earlier when symptomatic.
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Salwan et al. (2017) conducted a cross-sectional in Undiagnosed syncope or presyncope (n=72). Head-up tilt test (HUTT) with isoprenaline was evaluated on Positive diagnostic response for syncope. The head-up tilt test, utilizing baseline tilt followed by isoprenaline provocation, successfully yielded a positive diagnosis of vasovagal syncope in 62.5% of patients with unexplained syncope.
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