Key result
Gastroesophageal reflux disease was associated with an increased risk of atrial fibrillation (RR 1.39; 95% CI 1.33-1.45), which persisted after adjustment for cardiovascular risk factors.
Why the study?
Does the presence of GERD increase the risk of atrial fibrillation in adult ambulatory patients?
Population
163,627 adult patients who received ambulatory care in the National Capitol Area military health care system…
Comparison
Presence of gastroesophageal reflux disease… vs Absence of gastroesophageal reflux disease (GERD)
Design
Cohort
Authors
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Does not warrant AF screening changes in GERD; leaves open whether the association is causal.
Cohort (n=163,627)
Does the presence of GERD increase the risk of atrial fibrillation in adult ambulatory patients?
Relative Risk: 1.39 (95% CI 1.33–1.45)
Gastroesophageal reflux disease is independently associated with an increased risk of atrial fibrillation, suggesting a potential pathophysiological link.
Kunz et al. (2009) conducted a cohort in Atrial fibrillation (n=163,627). Gastroesophageal reflux disease (GERD) vs. Absence of GERD was evaluated on Diagnosis of atrial fibrillation (RR 1.39, 95% CI 1.33-1.45). Gastroesophageal reflux disease was associated with an increased risk of atrial fibrillation (RR 1.39; 95% CI 1.33-1.45), which persisted after adjustment for cardiovascular risk factors.
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