Key result
This review summarizes the current research progress on the mechanism, risk factors, and treatment of coronary artery damage in Kawasaki disease to improve long-term prognosis in children.
Why the study?
Coronary artery damage from Kawasaki disease is a common acquired heart disease risking severe cardiovascular sequelae, prompting a review to improve long-term vascular health management.
This review summarizes the mechanisms, risk factors, and treatments for coronary artery damage in children with Kawasaki disease to improve long-term vascular health management.
May aid Kawasaki disease management; leaves open need for prospective trials on optimal therapies.
Kawasaki Disease (KD) is a vasculitis of unknown etiology commonly seen in infants and children. Children with Kawasaki disease are at risk for serious cardiovascular sequelae, especially coronary artery abnormalities, which can lead to myocardial ischemia, myocardial infarction, and sudden death. Coronary artery lesions (CAL) caused by Kawasaki disease has become one of the common acquired heart diseases in children in some countries and regions. This article reviews the current research progress on the mechanism, risk factors and treatment of coronary artery damage in Kawasaki disease, aiming to improve the long-term prognosis of vascular health management in children with KD, in order to provide references for clinicians.
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Lü et al. (2023) conducted a review in Kawasaki Disease. This review summarizes the current research progress on the mechanism, risk factors, and treatment of coronary artery damage in Kawasaki disease to improve long-term prognosis in children.
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