Why the study?
Does a calcium channel blocker prevent recurrent attacks of amaurosis fugax suspected to be caused by vasospasm?
Does a calcium channel blocker prevent recurrent attacks of amaurosis fugax suspected to be caused by vasospasm?
Calcium channel blockers may be an effective treatment for amaurosis fugax caused by vasospasm.
May support calcium channel blocker trial in suspected vasospastic amaurosis fugax; leaves open efficacy confirmation in controlled studies.
Vasospasm may be one of the causes of amaurosis fugax. A patient is reported who daily experienced multiple brief episodes of amaurosis fugax. The absence of physical, laboratory, or radiographic evidence for thromboembolism, hemodynamic compromise, or vasculitis, suggested that the amaurosis might be caused by vasospasm. This hypothesis was supported by cessation of the attacks of amaurosis when the patient was treated with a calcium channel blocker.
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Winterkorn et al. (1991) studied this question.
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