Key result
Adolescents with a history of Kawasaki disease had significantly lower aerobic metabolism capacity and peak exercise load capacity than controls (p=0.021 and 0.043, respectively).
Why the study?
Children with Kawasaki disease show lower moderate-to-vigorous activity and exercise self-efficacy, which may adversely affect their cardiopulmonary function in adolescence.
Does a history of Kawasaki disease reduce cardiopulmonary function and exercise capacity in adolescents?
Population
Adolescents who once had KD and age- and sex-matched control adolescents
Comparison
Adolescents with prior KD vs age- and sex-matched controls
Design
Case-control study
Authors
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Adolescents with prior KD may have reduced aerobic capacity; this Level 5 observational finding leaves open whether exercise promotion improves outcomes.
Case-Control
Does a history of Kawasaki disease reduce cardiopulmonary function and exercise capacity in adolescents?
p-value: p=0.021 and 0.043
Adolescents with a history of Kawasaki disease exhibit significantly reduced aerobic metabolism and peak exercise capacity compared to healthy peers, highlighting the need for targeted exercise interventions.
Yang et al. (2020) conducted a case-control in Kawasaki disease. History of Kawasaki disease vs. Age- and sex-matched controls was evaluated on Aerobic metabolism capacity and peak exercise load capacity (p=0.021 and 0.043). Adolescents with a history of Kawasaki disease had significantly lower aerobic metabolism capacity and peak exercise load capacity than controls (p=0.021 and 0.043, respectively).
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