Key result
Anemia prevalence in patients with chronic obstructive pulmonary disease ranges from 7.5% to 33%, though its mechanisms and effective treatments remain controversial.
Why the study?
Although normochromic normocytic anemia is recognized in COPD with reported prevalence ranging from 7.5% to 33%, it remains unclear whether anemia is a systemic feature or comorbidity, and its mechanisms and treatment remain poorly understood.
This review highlights the variable prevalence of normochromic normocytic anemia in COPD patients and the need for further research into its mechanisms and treatment.
Anemia occurs in up to one-third of COPD patients; leaves open whether it is a systemic feature or comorbidity.
Until recently, compensatory erythrocytosis related to impaired renal blood circulation, treatment with some pharmacological agent, smoking, etc., was considered as one of the obligatory signs of advanced chronic obstructive pulmonary disease (COPD). Currently, normochromic normocytic anemia in COPD patients was diagnosed according to results of several studies. Prevalence data on anemia in COPD differ significantly from 7.5% to 33%. It is unclear, if anemia is a systemic feature of COPD or comorbidity. This article is a review about relationship between COPD and anemia. Most authors consider anemia in COPD as a condition associated with chronic disease, but mechanisms of its development are not fully investigated. There are few studies of effective treatment of anemia in COPD and their results are controversial. New experimental and clinical studies on mechanisms of anemia in COPD are required to improve management of such patients, their quality of life and outcomes.
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Zhusina et al. (2019) conducted a review in Chronic obstructive pulmonary disease (COPD) and anemia. Anemia was evaluated. Anemia prevalence in patients with chronic obstructive pulmonary disease ranges from 7.5% to 33%, though its mechanisms and effective treatments remain controversial.
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