Key result
Prehypertension with higher hsCRP levels was associated with an increased risk of ischemic stroke compared to normotension with lower hsCRP levels (HR 2.63; 95% CI 1.11-6.24).
Why the study?
Does elevated hsCRP predict an increased risk of ischemic stroke in subjects with prehypertension?
Cohort (n=22,676)
Does elevated hsCRP predict an increased risk of ischemic stroke in subjects with prehypertension?
Hazard Ratio: 2.63 (95% CI 1.11–6.24)
Elevated hsCRP identifies a high-risk subtype of prehypertension associated with an increased short-term risk of ischemic stroke.
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Elevated hsCRP may flag higher-risk prehypertension; leaves open whether inflammation-targeted interventions reduce stroke incidence.
Tanaka et al. (2010) conducted a cohort in Prehypertension (n=22,676). Prehypertension with higher hsCRP levels vs. Normotension with lower hsCRP levels was evaluated on incidence of ischemic stroke (HR 2.63, 95% CI 1.11-6.24). Prehypertension with higher hsCRP levels was associated with an increased risk of ischemic stroke compared to normotension with lower hsCRP levels (HR 2.63; 95% CI 1.11-6.24).
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