The Relationship of Chronic Ulcerative Colitis and Cirrhosis

Article1 August 1953THE RELATIONSHIP OF CHRONIC ULCERATIVE COLITIS AND CIRRHOSISF. W. HOFFBAUER, M.D., J. S. MCCARTNEY, M.D., CLARENCE DENNIS, M.D., KARL KARLSON, M.D.F. W. HOFFBAUER, M.D.Search for more papers by this author, J. S. MCCARTNEY, M.D.Search for more papers by this author, CLARENCE DENNIS, M.D.Search for more papers by this author, KARL KARLSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-2-267 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe etiology of idiopathic ulcerative colitis is obscure; the same statement applies equally well to most types of human cirrhosis. The occurrence of two such diseases in the same patient raises the question, is there any possible relationship between the two disorders? The occurrence of cirrhosis and the existence of hepatic insufficiency in patients with chronic ulcerative colitis are by no means unknown. Comfort, Bargen and Morlock1in 1938 called attention to this association in a report of four cases. Tumen, Monaghan and Jobb2in 1947 described five patients who exhibited hepatic cirrhosis as a complication of chronic ulcerative colitis....Bibliography1. ComfortBargenMorlock MWJAC: The association of chronic ulcerative colitis (colitis gravis) with hepatic insufficiency: report of four cases, M. Clin. North America 22: 1089, 1938. CrossrefGoogle Scholar2. TumenMonaghanJobb HJJFE: Hepatic cirrhosis as a complication of chronic ulcerative colitis, Ann. Int. Med. 26: 542, 1947. LinkGoogle Scholar3. PollardBlock HMM: Association of hepatic insufficiency with chronic ulcerative colitis, Arch. Int. Med. 82: 159, 1948. CrossrefGoogle Scholar4. JonesBaggenstossBargen GWAHJA: The liver in chronic ulcerative colitis, Proc. Staff Meet. Mayo Clin. 25: 251, 1950. Google Scholar5. JonesBaggenstossBargen GWAHJA: Hepatic lesions and dysfunction associated with chronic ulcerative colitis, Am. J. M. Sc. 221: 279, 1951. CrossrefMedlineGoogle Scholar6. KlecknerStaufferBargenDockerty MSMHJAMB: Hepatic lesions in the living patient with chronic ulcerative colitis as demonstrated by needle biopsy, Gastroenterology 22: 13, 1952. CrossrefMedlineGoogle Scholar7. Case Records of the Massachusetts General Hospital: Case 30491, Ulcerative colitis, involving entire colon and distal ileum; acute hemorrhagic hepatitis, superimposed on toxic cirrhosis, New England J. Med. 231: 771, 1944. CrossrefGoogle Scholar8. Case Records of the Massachusetts General Hospital: Case 34432, Chronic ulcerative colitis, severe; cirrhosis of liver, toxic type; acute glomerulonephritis, New England J. Med. 239: 635, 1948. CrossrefMedlineGoogle Scholar9. Case Records of the Massachusetts General Hospital: Case 35101, Ulcerative colitis, chronic; cirrhosis of liver, post-atrophy type, New England J. Med. 240: 384, 1949. CrossrefMedlineGoogle Scholar10. Case Records of the Massachusetts General Hospital: Case 35102, Chronic ulcerative colitis, with pseudopolyposis and adenocarcinoma, portal cirrhosis, post-atrophy type, New England J. Med. 240: 388, 1949. MedlineGoogle Scholar11. RossSwarts JRJM: Hepatic dysfunction and cirrhosis in chronic ulcerative colitis, Gastroenterology 10: 81, 1948. MedlineGoogle Scholar12. KimmelstielLargeVerner PHLHD: Liver damage in ulcerative colitis, Am. J. Path. 28: 259, 1952. MedlineGoogle Scholar13. Goldblatt H: Report of pathologists on cirrhosis study. Liver Injury, Trans. Sixth Conf. New York, Josiah Macy, Jr. Foundation, 1947 (p. 9). Google Scholar14. Hartroft WS: Diagnostic significance of fatty cysts in cirrhosis, Arch. Path. 55: 63, 1953. Google Scholar15. HoffbauerWittenburg FWB: Dietary hepatic necrosis: absence of cirrhosis following recurrent episodes, Federation Proc. 12: 392, 1953. Google Scholar16. Stokes J: Viral hepatitis, Am. J. M. Sc. 225: 349, 1953. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Presented in abstract form at the Thirty-Fourth Annual Session of the American College of Physicians, Atlantic City, April 15, 1953.From the Departments of Medicine, Pathology and Surgery, University of Minnesota Medical School, Minneapolis. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRight-sided or segmental ulcerative colitisPractical points in the pathology and surgical treatment of ulcerative colitis. A critical reviewSystemische KomplikationenLiver Disease in Ulcerative Colitis I. Analysis of Operative Liver Biopsy in 138 Consecutive Patients Having ColectomyM. N. EADE, M.B., M.D., M.R.A.C.P.PORTAL BACTERÆMIA IN CASES OF ULCERATIVE COLITIS SUBMITTED TO COLECTOMYColitis ulcerosaLupus erythematosus cell phenomenon in patients with chronic ulcerative colitisDisease of the liver in chronic ulcerative colitisChronic liver disease in young peopleTHE LIVER IN ULCERATIVE DISEASE OF THE INTESTINAL TRACT: FUNCTIONAL AND ANATOMIC CHANGES*ARNOLD S. MONTO, M.D.Hepatitis, colitis, and lupus manifestationsPathologic aspects of cirrhosisPhysiological Considerations in the Management of Idiopathic Ulcerative ColitisUlcerative Colitis in Cirrhosis of the LiverThe natural history of ulcerative colitisUlcerative colitisThe Liver in Regional EnteritisDie Colitis UlcerosaSubclinical hepatic diseaseCurrent pediatric references 1 August 1953Volume 39, Issue 2Page: 267-284KeywordsCirrhosisEtiologySurgeryUlcerative colitis ePublished: 1 December 2008 Issue Published: 1 August 1953 PDF downloadLoading ...