Key result
The etiology of mitral valve regurgitation determines the outcome of mitral valve repair, with myxomatous disease showing 90% freedom from reoperation at 10 years compared to 63% for functional and 66% for rheumatic disease.
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The etiology of mitral valve disease strongly predicts the long-term success of mitral valve repair, with myxomatous disease showing the best outcomes and functional or rheumatic disease having higher rates of reoperation.
The first successful mitral valve repair was performed by Elliot Cutler at Brigham and Women's Hospital in 1923. Subsequent evolution in the surgical techniques as well as multi-disciplinary cooperation between cardiac surgeons, cardiologists and cardiac anesthesiologists has resulted in excellent outcomes. In spite of this, the etiology of mitral valve pathology ultimately determines the outcome of mitral valve repair.
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Cohn et al. (2015) conducted a review in Mitral valve regurgitation (n=1,503). Mitral valve repair was evaluated on 30-day mortality and long-term freedom from reoperation. The etiology of mitral valve regurgitation determines the outcome of mitral valve repair, with myxomatous disease showing 90% freedom from reoperation at 10 years compared to 63% for functional and 66% for rheumatic disease.
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