Key result
Surgical resection of an extremely rare anterior mediastinal leiomyosarcoma originating from a bronchogenic cyst in an 82-year-old woman was followed by tumor recurrence at 24 months.
Why the study?
Mediastinal leiomyosarcoma is an aggressive tumor primarily occurring in the posterior mediastinum, and reports of anterior mediastinal leiomyosarcoma originating from a bronchogenic cyst are extremely rare.
Case Report (n=1)
No
This case report highlights an extremely rare presentation of an anterior mediastinal leiomyosarcoma originating from a bronchogenic cyst.
Answers are grounded in this paper and cite their sources.
May prompt inclusion of leiomyosarcoma in bronchogenic cyst differentials; leaves open frequency of malignant transformation.
Mediastinal leiomyosarcoma is an aggressive tumor that primarily occurs in the posterior mediastinum. A bronchogenic cyst is a benign lesion that often develops in the mediastinum close to the thoracic trachea and has been reported to be the origin of certain malignancies. The present study reports an extremely rare case of an anterior mediastinal leiomyosarcoma that was considered to have originated from a bronchogenic cyst. An 82-year-old woman complained of chest pain, presenting an abnormal 70 mm mass shadow in the anterior mediastinum of a chest CT scan. Mediastinal tumor resection was performed and the tumor was diagnosed as a leiomyosarcoma. As the tumor was located adjacent to a bronchogenic cyst, it was considered to have originated from the remnant tissue of the cyst. Recurrent lesions were noted in the right lower lobe on CT scan 24 months after surgery.
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Kimura et al. (2020) conducted a case report in Anterior mediastinal leiomyosarcoma (n=1). Mediastinal tumor resection was evaluated on Tumor recurrence. Surgical resection of an extremely rare anterior mediastinal leiomyosarcoma originating from a bronchogenic cyst in an 82-year-old woman was followed by tumor recurrence at 24 months.
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