What question did this study set out to answer?

To investigate the source and transmission dynamics of a cluster of acute hepatitis E virus infections identified among passengers returning from a world cruise.

October 23, 2009Emerging infectious diseasesOpen Access

Hepatitis E Outbreak on Cruise Ship

View Full Paper

Ask AI

Bookmark

To investigate the source and transmission dynamics of a cluster of acute hepatitis E virus infections identified among passengers returning from a world cruise.
Conducted an epidemiologic outbreak investigation collecting and testing blood samples from 789 passengers.
Performed serologic testing for hepatitis E virus IgM and IgG antibodies alongside viral RNA sequencing on confirmed cases to determine viral genotype.
Serologic analysis identified 195 of 789 passengers (25%) as seropositive, with 33 (4%) demonstrating IgM indicative of recent acute infection (11 symptomatic) and 162 (21%) showing IgG indicative of past infection.
Most acutely infected passengers were male (25/33, 76%), and viral RNA sequencing confirmed hepatitis E virus genotype 3 closely homologous to European strains.
Acute infection was significantly associated with consuming shellfish on board (OR 4.27, 95% CI 1.23–26.94, p = 0.019), male sex, and alcohol consumption.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Epidemiologic investigation reveals shellfish consumption as an exposure linked to acute hepatitis E infection on a cruise ship, indicating a foodborne outbreak.

Cite This Study

Said et al. (2009) studied this question.

synapsesocial.com/papers/6a93b3771932af70b4806123 https://doi.org/10.3201/eid1511.091094

View Full Paper

Ask AI

Bookmark

Implication

Epidemiologic investigation reveals shellfish consumption as an exposure linked to acute hepatitis E infection on a cruise ship, indicating a foodborne outbreak.

Hepatitis E Outbreak on Cruise Ship

Key Points

Discussion

Implication

Cite This Study

Hepatitis E Outbreak on Cruise Ship

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider