Key result
A 35-year-old pregnant female with renal Ewing sarcoma presented with a gently progressive mass and elevated mean corpuscular volume and lactate dehydrogenase, ultimately expiring from metastases.
Why the study?
Extra-skeletal Ewing's sarcoma is rare in adults, and its primary site dictates signs and symptoms, leading to compromised early treatment when more common tumors are prioritized as differentials.
Case Report (n=1)
Renal Ewing's sarcoma is a rare, aggressive tumor that can present subtly and requires careful evaluation of any parenchymal or cortical thickening in primary imaging.
Renal Ewing sarcoma in pregnancy remains rare; this case extends sparse reports but leaves optimal management open.
Extra-skeletal Ewing's sarcoma is among the rarest tumors in adults. The primary sites of the tumor dictates symptoms and signs, thus early treatments are compromised when more common tumors are lined up as differentials by the location. We present a case of a 35-year-old pregnant female who developed a renal Ewing sarcoma during pregnancy. A prior simple left kidney cyst in an ultrasound with no tumor signs was spotted. A month after her cesarean section she visited a doctor when she was sent and admitted for surgery with renal cell carcinoma as the primary diagnosis to the Firoozgar hospital. Histology confirmed the final diagnosis. To this end, she completed the standard chemotherapy for the renal Ewing sarcoma with pulmonary metastasis when she was re-evaluated for the general bone pain, diagnosed with multiple bone metastases, and ultimately approached her palliative care. She expired after 2 months. This study demonstrates: a gently progressive mass; palpable in late stages; introduced rise in mean corpuscular volume and lactate dehydrogenase with no drop in the hematocrit. In conclusion, any random parenchymal and/or cortical thickening in primary ultrasound and/or computed tomography demonstrating a cyst-whether displaying internal echo or not- with suggested signs should be furtherly evaluated.
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Babapour et al. (2020) conducted a case report in Renal Ewing's sarcoma (n=1). A 35-year-old pregnant female with renal Ewing sarcoma presented with a gently progressive mass and elevated mean corpuscular volume and lactate dehydrogenase, ultimately expiring from metastases.
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