Key result
Surgical excision without adjuvant chemotherapy resulted in the patient remaining disease-free at 30 months post-nephrectomy for primary renal Ewing's sarcoma.
Case Report (n=1)
No
This case report demonstrates that localized primary renal Ewing's sarcoma can potentially be managed successfully with surgical excision alone, achieving 30 months of disease-free survival without chemotherapy.
May support surgery alone for localized renal Ewing sarcoma; leaves open adjuvant chemotherapy role pending larger studies.
INTRODUCTION: Primary renal Ewing's sarcoma is a rare tumor with dismal prognosis. The main treatment modality of treatment is surgical excision with adjuvant or neoadjuvant chemotherapy. CASE PRESENTATION: We present a case of primary renal EWS in 27-year-old male. He presented to our center complaining of three days history of severe left flank pain associated with nausea and vomiting. Computerized tomography (CT) revealed a 10 × 7 × 6.5 cm left lower pole renal mass. Left radical nephrectomy was performed and revealed a tumor with uniform round to oval nuclei cells. The cells stained strongly positive for CD 99. The diagnosis was established as primary renal Ewing's sarcoma. The patient refused the chemotherapy. Fortunately, he was free of the disease on regular clinical and radiological follow-up, the last follow up was 30 months post-nephrectomy. CONCLUSION: This case highlights the importance of proper surgical treatment and its role in the managing this type of malignancy especially in localized disease at presentation.
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Abdalla et al. (2019) conducted a case report in Primary renal Ewing's sarcoma (n=1). Surgical excision (left radical nephrectomy) was evaluated on Disease recurrence. Surgical excision without adjuvant chemotherapy resulted in the patient remaining disease-free at 30 months post-nephrectomy for primary renal Ewing's sarcoma.
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