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Introduction Ewing sarcoma is classically considered to be an osseous tumor. Soft tissue Ewing sarcoma is rare and less likely to have associated clinical symptoms. Case Presentation Here we report the case of an 8 year old male patient presenting for 2 months of hematuria and associated left flank pain who was found to have a tumor of the left kidney initially identified by computed tomography (CT). Resection of the tumor was completed via left total nephrectomy; pathology from the MayoComplete Solid Tumor Panel revealed Ewing sarcoma. Following resection, the patient underwent 27 cycles of chemotherapy, with radiotherapy initiated on week 13 of treatment. Post-treatment positron emission tomography (PET) scans at 6 and 10 months post-treatment have shown resolution of the disease. Conclusion Surgical resection followed by chemotherapy plus radiotherapy seems to be an efficient treatment for non-metastatic renal Ewing sarcoma in children in the short term.
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Schanz et al. (2026) studied this question.
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