Why the study?
Does surgical resection and combination chemotherapy prevent recurrence in a patient with extraskeletal Ewing's sarcoma of the chest wall?
Does surgical resection and combination chemotherapy prevent recurrence in a patient with extraskeletal Ewing's sarcoma of the chest wall?
Surgical resection combined with chemotherapy resulted in no recurrence at 2.5 years in a rare case of extraskeletal Ewing's sarcoma of the chest wall.
Supports multimodality therapy consideration in rare chest wall Ewing sarcoma; leaves open need for prospective data.
We describe a rare case of extraskeletal Ewing sarcoma of the chest wall. The patient, a 30-yaer-old woman, was seen at the hospital because of right back pain and an abnormal shadow in the right chest wall on X-ray, CT, and MRI films. CT and MRI revealed a solid tumor attached to the posteroinferior aspect of the intrathoracic chest wall. Angiography of intercostal arteries disclosed feeding arteries from the sixth and seventh intercostal arteies, and a tumor stain. We suspected a sarcoma, and surgically resected a tumor in the sixth intercostal space with the sixth and seventh ribs en bloc. The tumor measured 4.0×2.5cm. Histologically, there was a little involvement of the ribs. Individual tumor cells were small and round-shaped, with scanty, ill-defined, PAS positive material in the cytoplasma. With these results, we made a diagnosis of extraskeletal Ewing's sarcoma. Combination chemotherapy with ADR, CPM, ACT-D and VCR was administered after the operation. Tegafur and PSK were orally administered after discharge. There has been no evidence of recurrence after two and a half years of follow-up.
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Yamamoto et al. (1998) studied this question.
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