All articles of this category The synthesis of N -acetyl-1,2-didehydrodopamine ( 6 ; N -acetyl-3,4-dihydroxystyrylamine) was accomplished by demethylation of N -acetyl-3,4-dimethoxystyrylamine ( 5 ), formed by sequential treatment of 3,4-dimethoxycinnamic acid ( 1 ) with thionyl chloride, sodium azide, heat and methyl magnesium bromide.
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Ramamurthy et al. (1987) studied this question.