Key result
Psychological processes such as depression, stress, and anxiety form a psychosomatic vicious circle with inflammatory and neuro-humoral factors, mediating myocardial infarction development.
Highlights the importance of a biopsychosocial approach and individualized rehabilitation in myocardial infarction by detailing the bidirectional psychosomatic links involving stress, anxiety, and depression.
The review presents recent studies demonstrating somatic shifts in psychological processes regarded as the risk factors for myocardial infarction: depression, stress, anxiety. Based upon a metaphorical term “a perfect storm”, inflammatory, immunological, neuro-humoral predisposing factors are presented, important for myocardial infarction development, as such shifts themselves, which are the somatic substrate for psychological states mediating myocardial infarction development through behavioral and biological risk factors: “sickness behavior”, “depression illness”. Both directions complete a vicious circle of psychosomatic changes. The emphasis is set on the importance of individual approach to rehabilitation and secondary prevention of myocardial infarction, as, from biopsychosocial point of view, the bottom-up and top-down psychosomatic links are unique for any patient.
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Таратухин et al. (2018) conducted a review in Myocardial infarction. Psychological processes (depression, stress, anxiety) was evaluated. Psychological processes such as depression, stress, and anxiety form a psychosomatic vicious circle with inflammatory and neuro-humoral factors, mediating myocardial infarction development.
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