Key result
Experimental infection with the DAstV-SDWF isolate, which shares 91.6%-98.6% genomic homology with other DAstV-1 strains, successfully reproduced clinical symptoms of duck viral hepatitis.
Why the study?
A highly acute hepatitis disease broke out in immunized ducklings in Shandong Province in March 2021, prompting the isolation and characterization of the emerging causative agent.
Population
Ducklings immunized against duck viral hepatitis vaccine in Shandong Province
Design
Experimental isolation, genomic characterization, and infection study
Authors
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Provides experimental model for DAstV-1 hepatitis; extends strain data but leaves open epidemiological and control questions.
The isolation and experimental infection of the DAstV-SDWF strain demonstrate that Duck astrovirus type-1 is a causative agent of duck viral hepatitis in China.
Wei et al. (2021) studied Duck viral hepatitis. DAstV-SDWF isolate experimental infection was evaluated on Genomic homology and reproduction of clinical symptoms. Experimental infection with the DAstV-SDWF isolate, which shares 91.6%-98.6% genomic homology with other DAstV-1 strains, successfully reproduced clinical symptoms of duck viral hepatitis.
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