Key result
Serial chicken-to-chicken passages of a novel chicken astrovirus isolate induced decreased weight gain and cystic lesions in the small intestine, reproducing clinical runting-stunting syndrome.
Population
1-day-old broiler chickens and LMH liver cell line
Design
Preclinical
Authors
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Supports astrovirus causality in broiler syndrome; leaves open field validation for diagnostics and control.
This study identifies a novel chicken astrovirus as an aetiological agent of runting-stunting syndrome in broiler chickens.
Kang et al. (2018) studied Runting-stunting syndrome (RSS). Chicken astrovirus (CkAstV) infection and serial passages was evaluated on Induction of clinical RSS (decreased weight gain and cystic lesions in the small intestine). Serial chicken-to-chicken passages of a novel chicken astrovirus isolate induced decreased weight gain and cystic lesions in the small intestine, reproducing clinical runting-stunting syndrome.