Key result
Four IBV isolates were detected in vaccinated chickens, with two related to Mass reference strains and two related to Egyptian variant 2 strains, indicating continuous viral evolution despite vaccination.
Observational (n=17)
Yes
The study demonstrates the continuous evolution of Egyptian IBV circulating in chickens despite the use of H120 live attenuated vaccine.
Vaccine updates may be needed against evolving IBV; leaves open optimal control strategies in Egyptian poultry.
Tracheal swabs and different organs are collected from 17 chicken farms showing respiratory signs and variable mortalities in different governorates. Three successive blind serial passages were performed. Four IBV isolates are detected in vaccinated chickens by RT-PCR and are identified by sequence and phylogenetic analysis of portion of Si gene. Two IBV isolates, IBV S40 and IBV S61 are related to Mass reference strains (Egypt/F/03, M41, H120, Ma5, and M52). However, IBV S78 and IBV S82 are related to Egyptian variant 2 IBV strains Ck/Eg/BSU-2/2011 and Ck/Eg/ BSU-3/201 1.These results indicate the continuous evolution of Egyptian IBV circulating in chickens despite vaccination using H120 live attenuated vaccine.
No takes yet. Share an insight, caveat, or question.
Ghetas et al. (2016) conducted an observational in Infectious Bronchitis Virus (IBV) infection in chickens (n=17). IBV isolation and molecular identification was evaluated on Detection and identification of IBV isolates. Four IBV isolates were detected in vaccinated chickens, with two related to Mass reference strains and two related to Egyptian variant 2 strains, indicating continuous viral evolution despite vaccination.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: