Key result
A novel approach using instantaneous flow fields avoids the overestimation of blood damage (hemolysis) that occurs when using Reynolds shear stress as a damaging parameter.
Population
Computational model of turbulent flow in a bileaflet mechanical heart valve
Comparison
Novel approach based on the generation of… vs Averaged pathlines based on mean velocity field…
Design
Preclinical
Authors
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May refine hemolysis prediction in valve simulations; challenges Reynolds shear stress models but leaves open clinical validation.
A novel computational approach demonstrates that using Reynolds shear stress as a damaging parameter overestimates hemolysis in mechanical heart valves and should be avoided.
Goubergrits et al. (2016) studied Hemolysis in mechanical heart valves. Instantaneous flow fields approach vs. Reynolds shear stress (RSS) approach was evaluated on Blood damage index (hemolysis). A novel approach using instantaneous flow fields avoids the overestimation of blood damage (hemolysis) that occurs when using Reynolds shear stress as a damaging parameter.
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