Key result
Cardiac MRI confirmed apical hypertrophic cardiomyopathy in a 27-year-old non-East Asian male presenting with episodic chest pain and giant inverted T-waves, mimicking acute coronary syndrome.
Why the study?
Chest pain in young adults poses a diagnostic challenge, often raising concerns for acute coronary syndrome, and conditions like apical hypertrophic cardiomyopathy can otherwise be misdiagnosed.
Case Report (n=1)
Cardiac MRI is a crucial diagnostic tool for identifying apical hypertrophic cardiomyopathy in young patients presenting with chest pain and giant inverted T-waves, helping to avoid unnecessary invasive procedures.
Clinicians should consider apical HCM in atypical ACS presentations regardless of ethnicity; this Level 5 report leaves open broader prevalence questions.
Chest pain in young adults can pose a diagnostic challenge, often raising concerns for acute coronary syndrome but more commonly resulting from non-cardiac causes. We report a case of apical hypertrophic cardiomyopathy (ApHCM) in a 27-year-old man, presenting with episodic chest pain and striking ECG abnormalities but normal coronary angiography. This case underscores the value of recognizing characteristic ECG patterns and the role of cardiac MRI in confirming ApHCM, a rare but clinically significant condition that can otherwise be misdiagnosed. Awareness of these findings in young patients without traditional cardiovascular risk factors is essential, as early MRI can establish the diagnosis and prevent unnecessary invasive procedures.
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Rehman et al. (2025) conducted a case report in Apical hypertrophic cardiomyopathy (n=1). Cardiac MRI was evaluated on Diagnosis of apical hypertrophic cardiomyopathy. Cardiac MRI confirmed apical hypertrophic cardiomyopathy in a 27-year-old non-East Asian male presenting with episodic chest pain and giant inverted T-waves, mimicking acute coronary syndrome.
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