Key result
Tear dominance, an absolute area difference >1.2 cm2 between proximal and distal entry tears at subacute CT angiography, strongly predicted long-term adverse aortic events (HR 5.2).
Why the study?
To identify entry tear variables related to adverse clinical events using CT angiography performed during the subacute phase of aortic dissection.
Do entry tear variables at CT angiography predict long-term adverse clinical events in patients with aortic dissection?
Population
72 participants with aortic dissection with a patent false lumen and no comorbidities
Comparison
Entry tear variables and maximum aortic diameter on subacute CTA
Design
Prospective study
Follow-up
9.22 years ± 5.78
Authors
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Entry tear features on subacute CTA associate with AAEs in patent false-lumen dissection; leaves open whether they refine risk stratification.
Cohort (n=72)
No
Do entry tear variables at CT angiography predict long-term adverse clinical events in patients with aortic dissection?
Hazard Ratio: 5.2 (95% CI 2.1–13)
p-value: p=<0.001
Tear dominance on subacute CT angiography, along with maximum aortic diameter and genetic aortic disease, strongly predicts long-term adverse events in patients with aortic dissection.
Cuellar et al. (2021) conducted a cohort in Aortic dissection with a patent false lumen (n=72). Tear dominance (absolute tear area difference > 1.2 cm2) vs. Balanced tears (tear area difference ≤ 1.2 cm2) was evaluated on Adverse aortic event (AAE) (HR 5.2, 95% CI 2.1-13, p=<0.001). Tear dominance, an absolute area difference >1.2 cm2 between proximal and distal entry tears at subacute CT angiography, strongly predicted long-term adverse aortic events (HR 5.2).
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