Key result
Age (P=0.005), hypertension (P=0.029), and primary entry tear proximal to the left subclavian aorta (P=0.036) were negative predictors for the degree of false lumen thrombosis after TEVAR.
Why the study?
Thrombosis of the false lumen is an important indicator of positive vascular remodeling after TEVAR for Stanford type B aortic dissection, prompting analysis of clinical factors affecting this thrombosis.
What clinical factors predict the degree of false lumen thrombosis after TEVAR in male patients with complicated Stanford type B aortic dissection?
Observational (n=52)
What clinical factors predict the degree of false lumen thrombosis after TEVAR in male patients with complicated Stanford type B aortic dissection?
Age, hypertension, and a primary entry tear proximal to the left subclavian artery are negative predictors of complete false lumen thrombosis after TEVAR in men with complicated type B aortic dissection.
May inform post-TEVAR risk stratification in complex TBAD; leaves open causal roles pending prospective validation.
Background Thrombosis of false lumen is considered as an important indicator in positive vascular remodeling of Stanford type B aortic dissection (TBAD) after thoracic endovascular aortic repair (TEVAR). Objectives Analysis of clinical factors affecting false lumen thrombosis after TEVAR in patients with complex TBAD. Methods A total of 52 male patients diagnosed with complex TBAD between January 2018 and December 2021 were included in the study. Based on the degree of thrombosis, subjects were categorized into a complete pseudocavity thrombosis group and partial pseudocavity thrombosis group. Analyses were performed using t-tests, chi-square or Fisher's exact tests, and multivariable logistic regression models. P<0.05 indicates that the difference is statistically significant. Results No significant difference was observed between the complete and partial false lumen thrombosis groups in the baseline parameters such as body mass index (BMI), hemoglobin (Hb), serum albumin (ALB), neutrophil to lymphocyte ratio (NLR) and other characteristics. Statistical analysis revealed that age ( P < 0.001), hypertension ( P = 0.033), primary entry tear proximal to the left subclavian aorta (LSA) ( P = 0.025) and early appearance of typical symptom ( P = 0.046) might be important influencing factor of the degree of thrombosis in false lumen after TEVAR. In addition, the age ( P =0.005), hypertension ( P =0.029) and primary entry tear proximal to LSA ( P =0.036) might be negative predictors to for the degree of thrombosis in false lumen in complicated TBAD male patients after TEVAR. Conclusions Age, hypertension, and primary entrance tear proximal to the LSA are potential predictors of the degree of thrombosis in male patients with TBAD after TEVAR.
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Yan et al. (2025) conducted an observational in Complex Stanford type B aortic dissection (TBAD) (n=52). Clinical factors (age, hypertension, primary entry tear location) was evaluated on Degree of thrombosis in false lumen (complete vs partial pseudocavity thrombosis). Age (P=0.005), hypertension (P=0.029), and primary entry tear proximal to the left subclavian aorta (P=0.036) were negative predictors for the degree of false lumen thrombosis after TEVAR.
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