Key result
The simultaneous use of an intra-aortic balloon combined with a BioMedicus pump restored pulsatility and increased coronary and carotid blood flows compared to the pump alone in a pig model.
Why the study?
Does the addition of an intra-aortic balloon pump to a BioMedicus left ventricular assistance device improve regional blood flows and pulsatility in a pig model?
Population
12 pigs in an experimental model of BioMedicus left ventricular assistance
Comparison
Simultaneous use of a BioMedicus left… vs Basal experimental condition with a full-flow…
Design
Preclinical
Authors
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May warrant human trials of combined IABP and centrifugal LVAD; leaves open clinical translation of restored pulsatility.
Does the addition of an intra-aortic balloon pump to a BioMedicus left ventricular assistance device improve regional blood flows and pulsatility in a pig model?
Combining an intra-aortic balloon pump with a centrifugal left ventricular assist device restores pulsatility and improves coronary and carotid blood flows in a preclinical model.
Collart et al. (2004) studied Experimental model of left ventricular assistance (n=12). Simultaneous use of BioMedicus pump and intra-aortic balloon pump vs. Full-flow BioMedicus pump alone was evaluated on Regional blood flows, pressure, and pulsatility. The simultaneous use of an intra-aortic balloon combined with a BioMedicus pump restored pulsatility and increased coronary and carotid blood flows compared to the pump alone in a pig model.
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