Key result
A consortium is developing a miniature mixed flow turbodynamic pediatric ventricular assist device featuring magnetic levitation for chronic support of children weighing 3 to 15 kg.
This review highlights the ongoing development of a novel pediatric ventricular assist device designed to provide chronic support for infants and young children with ventricular failure.
Addresses unmet need for chronic support in 3-15 kg children; leaves open clinical feasibility and outcomes of this device.
The very limited options available to treat ventricular failure in children with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device at the University of Pittsburgh (UoP) and University of Pittsburgh Medical Center (UPMC). Our effort involves a consortium consisting of UoP, Children's Hospital of Pittsburgh (CHP), Carnegie Mellon University, World Heart Corporation, and LaunchPoint Technologies, Inc. The overall aim of our program is to develop a highly reliable, biocompatible ventricular assist device (VAD) for chronic support (6 months) of the unique and high-risk population of children between 3 and 15 kg (patients from birth to 2 years of age). The innovative pediatric ventricular assist device we are developing is based on a miniature mixed flow turbodynamic pump featuring magnetic levitation, to assure minimal blood trauma and risk of thrombosis. This review article discusses the limitations of current pediatric cardiac assist treatment options and the work to date by our consortium toward the development of a pediatric VAD.
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Borovetz et al. (2006) conducted a review in Ventricular failure in children with congenital and acquired heart diseases. Pediatric ventricular assist device was evaluated. A consortium is developing a miniature mixed flow turbodynamic pediatric ventricular assist device featuring magnetic levitation for chronic support of children weighing 3 to 15 kg.
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